The AI Organ-on-Chip System represents a groundbreaking innovation in drug testing and biomedical research. By integrating microfluidics with artificial intelligence, this platform simulates human tissue functions on a chip, allowing researchers to assess organ responses to pharmaceutical compounds in real-time. Using advanced machine learning models, the system predicts drug efficacy and toxicity, providing invaluable insights into potential treatments. With capabilities to simulate heart, liver, and lung systems, this technology minimizes the reliance on animal testing, accelerates drug development, and enhances personalized medicine. The AI Organ-on-Chip System is poised to transform the landscape of therapeutic discovery and safety evaluations.